What is the best & safest anti-thyroid drugs to be administered during pregnancy

I went through some websites and books, and they pretty much contradict each other. Some says PTU, and the other sources recommend carbimazoles.

I'll be very happy to hear answers from anyone who can solve my confusion.

Authored By sukri nawi on Monday 18th February 2013

Responses

Anita Phung
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Medical Student - Kings College London
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Posted almost 7 years ago

I was taught that for pregnancy:

  • blockade regime, not block and replace regime.

  • PTU preferred for pregnancy

  • because side effects of carbimazole include aplasia cutis and choanal atresia, essentially mal

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Debkumar Chowdhury
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Clinical Fellow Surgery - West of Scotland
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Posted almost 7 years ago

As we all know that all anti-thyroid medications have a detrimental effect on the unborn child. PTU(Propylthiouracil) has been shown to have fewer side effects and to a lesser extent that the other medications. This is due to lower permeability of the

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R Hutch
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Posted almost 7 years ago

Methimazole (MMI) and propylthiouracil (PTU) may both be used during pregnancy; however, PTU is preferred in the first trimester and should be replaced by MMI after this trimester.

MMI is the mainstay of the treatment of post partum hyperthyroi

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Aaron Soares
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Posted almost 7 years ago

PTU is the best for a pregnant woman . Rest are avoided as a rule .

MMI is best for regular patients as its quicker in action and requires single dose per day .
PTU although has to be taken 2 or 3 times a day and takes longer to result in

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