What are the factors for regulation of erythropoeitin secretion?

What are the factors affecting erythropoeitin secretion?

Authored By Sandamaal Jayasekara on Saturday 30th March 2013

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Conrad Hayes
·
Medical Student - Keele
·
Posted over 7 years ago

They are called hypoxia-induced transcription factors (HIF). In the presence of oxygen they are hydroxylated. In hypoxia when there is less O2 they can't be hydroxylated and the stabilised molecule acts to increase transcription of EPO.

Thi

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