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Mortality Up With High-Normal HR, but Exercise Limits Effect

Life-span shortens even with beats per minute in the 80s or 90s, but "what I'm showing is by exercising, you reduce the mortality, and that's even more important than heart rate."  
medscape.com
over 3 years ago
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TAUSSIG Hints at Fewer CV Events on Evolocumab in Homozygous FH

No control group, but also no deaths and only four CV events in 1.7 years in 106 patients on the PCSK9 inhibitor. "Which is remarkable" in HoFH, says a researcher; still, all urge caution interpreting the results.  
medscape.com
over 3 years ago
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Management of a new pregnancy in a woman with chronic hypertension

At first presentation of a newly pregnant woman with chronic hypertension, arrange prompt referral to an obstetrician, preferably one specialising in hypertension  
feeds.bmj.com
over 3 years ago
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Would Brexit stop the flow of doctors and patients between EU countries?

In the last of a series on the implications for health of the UK leaving the European Union, Anne Gulland examines the likely effects on freedom of movement  
feeds.bmj.com
over 3 years ago
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Management of a new pregnancy in a woman with chronic hypertension

At first presentation of a newly pregnant woman with chronic hypertension, arrange prompt referral to an obstetrician, preferably one specialising in hypertension  
feeds.bmj.com
over 3 years ago
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Autosomal dominant polycystic kidney disease in children

Autosomal dominant polycystic kidney disease (ADPKD) was previously known as “adult PKD” because most cases come to medical attention during adulthood. However, clinically important morbidity such as hypertension and cardiovascular disease occurs much earlier. Screening children could detect those affected, and randomised controlled trials show that early intervention reduces disease progression. Despite this, very few children from families with the condition are currently assessed in the United Kingdom.  
feeds.bmj.com
over 3 years ago
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Long-term Survival After Cardiac Surgery in COPD Patients

How do COPD patients fare in the long-term after undergoing coronary artery bypass grafting?  
medscape.com
over 3 years ago
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Measurement of Oxygen Consumption in Critically Ill Children

How do these two methods for measuring oxygen consumption compare? Is one superior to the other?  
medscape.com
over 3 years ago
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Managing Pain in Frail Elders

We face barriers in the assessment, treatment and evaluation of pain in elders. Read how to overcome these barriers here.  
medscape.com
over 3 years ago
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Identifying Rare and Emerging Microbes Quickly

If your lab isn't using MicrobeNet, you are missing out on faster pathogen detection than is possible by conventional means.  
medscape.com
over 3 years ago
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Inflammation Drives Adverse LV Remodeling After Acute MI

How does activation of inflammatory pathways contribute to progressive adverse LV remodeling after acute MI?  
medscape.com
over 3 years ago
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Trimethylamine N-oxide and Prognosis in Acute Heart Failure

Might plasma levels of the gut-derived metabolite trimethylamine N-oxide have utility as a prognostic marker in acute heart failure?  
medscape.com
over 3 years ago
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Renal Replacement Therapy -- Sooner or Later?

Should renal replacement therapy be initiated early to improve outcomes?  
medscape.com
over 3 years ago
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Clinical Challenges in Relapsed/Refractory Hodgkin Lymphoma

Apply your knowledge to 2 clinical case challenges in relapsed/refractory Hodgkin lymphoma.  
medscape.org
over 3 years ago
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Patients Prefer Physicians to Wear White Coats

Most patients prefer their dermatologists to wear a white coat, regardless of the clinic setting, a new survey suggests.  
medscape.com
over 3 years ago
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Warn Patients About Risk From Antacids With Aspirin, FDA Says

The FDA has long warned about the risk for serious bleeding with OTC aspirin-containing antacids, but it still receives reports about this adverse event.  
medscape.com
over 3 years ago
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Initiative Curbs ED Urinary Catheterization in Febrile Kids

Screening of urine bag specimens for urinary tract infections (UTIs) can obviate catheterization in many very young febrile emergency department (ED) patients, according to Pennsylvania-based researchers.  
medscape.com
over 3 years ago
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Take a #SMACCselfie

If you want to win an exclusive* Don’t Forget The Bubbles t-shirt then take a #SMACCselfie displaying your DFTB badges, stickers or tattoos (yes, we have those too!) and tag #DFTB.  Each day one lucky winner, drawn at random, will win a t-shirt.  
dontforgetthebubbles.com
over 3 years ago
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Parechovirus

A 2 week old baby, Isabelle, is rushed into the emergency department by her frantic parents. She is tachycardic to 220bpm, febrile to 39.5°C, with a widespread, blanching red rash. She is screaming and looks very unwell. She is rushed into a resus bay and the septic workup begins…  
dontforgetthebubbles.com
over 3 years ago
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What exactly is an RCT and is this one any good? - INTENSIVE

In Part 1, Chris Nickson’s Nuts (and bolts of EBM) touched on the PICO question. When we have a clinical question, we look to see if it has been answered, focusing on specific patients, interventions, comparisons and outcomes.  
intensiveblog.com
over 3 years ago