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Dr Alastair Buick

Dr Alastair Buick

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Dr Alastair Buick

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I'm the founder of Meducation. I love to chat to Meducation members so please email me at al@meducation.net if you'd like to say hello!

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Type 1 diabetes and immune-based therapies

Despite major advances in understanding the immunopathology of type 1 diabetes, the promise of successful immune-based therapies has so far been unfulfilled. This two-paper Series from The Lancet Diabetes & Endocrinology covers the current challenges faced in the development of immune-based therapies for type 1 diabetes and approaches to overcome them in the future. In the first Series paper, Mark Atkinson and colleagues discuss the challenge of modulating β-cell autoimmunity in type 1 diabetes, highlighting how gaps in understanding of disease pathogenesis and issues with study design have hampered advances in translating initially promising preclinical approaches into clinical therapies, and recommending several approaches to advance progress in this area. In the second Series paper, Bart Roep and colleagues focus on antigen-specific immunotherapy approaches, highlighting recent research advances and the opportunities and challenges of translating research findings into clinical strategies that prevent progressive loss of β-cell function and survival in patients.  
thelancet.com
about 1 year ago
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How to taper opioids

Stream How to taper opioids by BMJ talk medicine from desktop or your mobile device  
soundcloud.com
about 1 year ago
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Lifestyle management of type 2 diabetes #351

Type 2 diabetes is a complex systems disease, caused by interactions between lifestyle and genes. It is an illusion to believe that it can be cured by medication. Lifestyle change should always be at the heart of treatment.  
soundcloud.com
about 1 year ago
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Deaf woman Joanne Milne hears for first time - BBC News

The moment a 39-year-old woman hears for the first time in her life, thanks to cochlear implants, is captured on video.  
BBC News
over 5 years ago
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How Much Does Lung Cancer Risk Drop When You Quit Smoking?

New study suggests that risk for lung cancer is highly persistent after quitting smoking, among former heavy smokers.  
medscape.org
11 months ago
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NHS facing biggest ever challenge, says new boss - BBC News

The NHS is facing the biggest challenge in its history because of the squeeze on its budget, says its new boss on his first day in the job.  
BBC News
over 5 years ago
National%20institute%20for%20health%20and%20care%20excellence%20(nice)?logotype=guidance
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Hypertension in adults: diagnosis and management | Guidance and guidelines | NICE

Evidence-based recommendations on the diagnosis and management of hypertension (high blood pressure) in adults  
nice.org.uk
over 1 year ago
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Healthy workplaces: improving employee mental and physical health and wellbeing | Guidance and guidelines | NICE

Evidence-based statements to deliver quality improvements in the health and wellbeing of all employees, including their mental health  
nice.org.uk
over 1 year ago
Www.bmj
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A third of GPs are considering retirement, BMA survey finds

A third of GPs in the United Kingdom are considering retiring from general practice in the next five years, a survey of the profession has found.  
bmj.com
over 4 years ago
National%20institute%20for%20health%20and%20care%20excellence%20(nice)?logotype=guidance
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Hypertension in pregnancy: diagnosis and management | Guidance and guidelines | NICE

Evidence-based recommendations on the diagnosis and management of hypertension (high blood pressure) in pregnancy  
nice.org.uk
over 1 year ago
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Nice Guidelines for Insomina

58 results for insomnia Sort: Relevance | Date  
nice.org.uk
over 1 year ago
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insomnia

 
cks.nice.org.uk
over 1 year ago
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Diabetic retinopathy - ruboxistaurin [ID382] | Guidance and guidelines | NICE

Diabetic retinopathy - ruboxistaurin [ID382]  
nice.org.uk
over 1 year ago
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TheLancet.com Homepage

For many complex reasons tuberculosis has the unenviable position of being the leading infectious cause of death, but a notable reason is that much about it is still unknown, particularly in relation to its transmission.  
thelancet.com
11 months ago
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Cardiology

View latest cardiology news, CME, clinical trial info, treatment guidelines, journal articles & more.  
epgonline.org
11 months ago
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The FFRangio System enables non-invasive, objective functional evaluation of multi-vessel coronary artery disease and receives FDA clearance.- CathWorks, 07-Jan-19

CathWorks announced that its FFRangio System received FDA 510(k) clearance. The FFRangio system demonstrated accuracy versus the invasive FFR wire...  
epgonline.org
11 months ago
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Venepuncture - how to take blood - OSCE Guide | Geeky Medics

A step by step guide to performing venepuncture in an OSCE setting, with an included video demonstration.  
geekymedics.com
about 2 years ago