Gross pathology of rheumatic heart disease.
Left ventricle has been cut open to display characteristic severe thickening of mitral valve, thickened chordae tendineae, and hypertrophied left ventricular myocardium. Autopsy.
These are essentially the same disorder. In children, the disease is rickets but after fusion of the epiphyseal plates it is known as osteomalacia. The most common cause is vitamin D deficiency. The condition is characterised by normal bone formation with abnormal bone mineralisation, thus there is excess osteoid and cartilage, and insufficient bone. Causes
The Calgary Guide is a compendium of flow-charts that link disease pathophysiology and disease manifestation. It is not a collection of summary notes, not a compiled list of answers to exam questions, and it contains no paragraphs or pages of text. Instead, the diagrams in The Calgary Guide connect the pathophysiology of diseases with their clinical findings and complications, explaining concisely and coherently the links in between.