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Www.bmj
1
14

Smoking bans are linked to reduction in preterm births and childhood asthma, says study

Rates of preterm births and paediatric hospital admissions for asthma fell by 10% within a year of smoke-free legislation taking effect, says a systematic review and meta-analysis on the issue.1  
bmj.com
over 7 years ago
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2
49

Asthma deaths report warns complacency is costing lives - BBC News

People with asthma are dying unnecessarily because of complacency among both medical staff and patients, a national study claims.  
BBC News
over 7 years ago
Www.bmj
1
15

Two thirds of deaths from asthma are preventable, confidential inquiry finds

Two in three deaths from asthma could be prevented by better management of the condition including personal asthma plans for patients, timely reviews of asthma care, and the prescription of more appropriate drugs, says the first confidential inquiry into asthma by the Royal College of Physicians.1  
www.bmj.com
over 7 years ago
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1
31

Asthma deaths report warns complacency is costing lives - BBC News

People with asthma are dying unnecessarily because of complacency among both medical staff and patients, a national study claims.  
BBC News
over 7 years ago
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1
28

Non-eosinophilic asthma

Stream Non-eosinophilic asthma by BMJ talk medicine from desktop or your mobile device  
SoundCloud
over 7 years ago
Www.bmj
1
43

Procedural sedation and analgesia for adults in the emergency department

A 59 year old woman presents to the emergency department with an isolated anterior dislocation of her left shoulder after a fall. Other than controlled asthma, she is healthy. Her last meal was four hours before the injury. After adequate analgesia using intravenous fentanyl, and despite an initial attempt to reduce her dislocation using relaxation techniques, it becomes evident that she needs sedation to complete the procedure successfully.  
bmj.com
over 7 years ago
Www.bmj
1
31

Procedural sedation and analgesia for adults in the emergency department

A 59 year old woman presents to the emergency department with an isolated anterior dislocation of her left shoulder after a fall. Other than controlled asthma, she is healthy. Her last meal was four hours before the injury. After adequate analgesia using intravenous fentanyl, and despite an initial attempt to reduce her dislocation using relaxation techniques, it becomes evident that she needs sedation to complete the procedure successfully.  
bmj.com
over 7 years ago
Www.bmj
1
45

Procedural sedation and analgesia for adults in the emergency department

A 59 year old woman presents to the emergency department with an isolated anterior dislocation of her left shoulder after a fall. Other than controlled asthma, she is healthy. Her last meal was four hours before the injury. After adequate analgesia using intravenous fentanyl, and despite an initial attempt to reduce her dislocation using relaxation techniques, it becomes evident that she needs sedation to complete the procedure successfully.  
bmj.com
over 7 years ago
Www.bmj
1
35

Procedural sedation and analgesia for adults in the emergency department

A 59 year old woman presents to the emergency department with an isolated anterior dislocation of her left shoulder after a fall. Other than controlled asthma, she is healthy. Her last meal was four hours before the injury. After adequate analgesia using intravenous fentanyl, and despite an initial attempt to reduce her dislocation using relaxation techniques, it becomes evident that she needs sedation to complete the procedure successfully.  
bmj.com
over 7 years ago
Preview
2
36

Comparative effectiveness of long term drug treatment strategies to prevent asthma exacerbations: network meta-analysis

Objective To determine the comparative effectiveness and safety of current maintenance strategies in preventing exacerbations of asthma.  
bmj.com
over 7 years ago
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1
14

Schools 'could struggle' with medical conditions policy - BBC News

Schools in England could struggle to implement new policies for children with medical conditions such as asthma, diabetes and cancer, head teachers say.  
BBC News
over 7 years ago
Www.bmj
1
26

Maintenance treatment for adults with chronic asthma

Which treatment for asthma is most likely to reduce the risk of exacerbations in adults? In a linked paper, Loymans and colleagues (doi:10.1136/bmj.g3009) seek to address this question using network meta-analysis.1 The authors identified and compared 16 different treatment approaches, using evidence from randomised trials of at least 24 weeks’ duration. The primary outcome was severe exacerbations (leading to admission to hospital, a visit to the emergency department, or a course of oral steroids).  
bmj.com
over 7 years ago
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1
17

Clinical trials: units of randomisation

Researchers evaluated the efficacy of a short course of oral prednisolone for acute asthma in children of school age. A randomised double blind placebo controlled crossover trial study design was used. The intervention was parent initiated treatment with the corticosteroid prednisolone (1 mg/kg/day) or placebo when an episode of acute asthma occurred. For each episode, treatment with prednisolone or placebo was chosen at random. Participants were 230 children aged 5-12 years with a history of recurrent episodes of acute asthma. Each child could contribute a maximum of eight episodes of acute asthma to the data collection over a three year study period.1  
bmj.com
over 7 years ago
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1
14

Clinical trials: units of randomisation

Researchers evaluated the efficacy of a short course of oral prednisolone for acute asthma in children of school age. A randomised double blind placebo controlled crossover trial study design was used. The intervention was parent initiated treatment with the corticosteroid prednisolone (1 mg/kg/day) or placebo when an episode of acute asthma occurred. For each episode, treatment with prednisolone or placebo was chosen at random. Participants were 230 children aged 5-12 years with a history of recurrent episodes of acute asthma. Each child could contribute a maximum of eight episodes of acute asthma to the data collection over a three year study period.1  
bmj.com
over 7 years ago
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5
115

Asthma death: Mother 'shattered' after ambulance delay - BBC News

A mother describes the pain of losing her daughter to asthma, when an ambulance went to the wrong address.  
BBC News
over 7 years ago
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1
27

Non-eosinophilic asthma

Stream Non-eosinophilic asthma by BMJ talk medicine from desktop or your mobile device  
SoundCloud
over 7 years ago
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1
18

The genomic origins of asthma

Stream The genomic origins of asthma by BMJ talk medicine from desktop or your mobile device  
SoundCloud
about 7 years ago
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1
51

Asthma: pathogenesis and novel drugs for treatment

Asthma affects almost 20 million people in the United States and more than 300 million people worldwide. Of these, 10-15% have severe asthma, which is refractory to commonly available drugs. New drugs are needed because those that are currently available cannot control symptoms and exacerbations in all patients and can cause adverse reactions. In the past 10 years, there have been substantial advances in the understanding of asthma genetics, airway biology, and immune cell signaling. These advances have led to the development of small molecule therapeutics and biologic agents that may improve asthma care in the future. Several new classes of asthma drugs—including ultra long acting β agonists and modulators of the interleukin 4 (IL-4), IL-5, IL-13, and IL-17 pathways—have been evaluated in randomized controlled trials. Other new drug classes—including dissociated corticosteroids, CXC chemokine receptor 2 antagonists, toll-like receptor 9 agonists, and tyrosine kinase inhibitors—remain in earlier phases of development. Despite some preliminary efficacy data, there is insufficient evidence to make strong recommendations about the use of these newer agents. Future research on the clinical efficacy of these biologic agents, the effect of newer agents on severe asthma in pediatric patients, and the biology of non-eosinophilic and corticosteroid resistant asthma is needed to reduce the morbidity of asthma worldwide.  
bmj.com
almost 7 years ago
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4
454

Asthma Pathophysiology

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YouTube
almost 7 years ago