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6

Tumour biomarkers: diagnostic, prognostic, and predictive

A 63 year old woman presented with a one month history of difficulty speaking and imbalance. She had been diagnosed with breast cancer two years earlier and had been treated with surgery, chemotherapy, and radiotherapy. This was followed by a year of trastuzumab (Herceptin) and continuous tamoxifen treatment.  
feeds.bmj.com
over 6 years ago
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10

Drug prescriptions rise in England - BBC News

An extra 34.5 million drugs and other prescription items were given out in 2014 compared to the year before, the latest snapshot for England shows.  
bbc.co.uk
over 6 years ago
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7

'Softener' may help kill cancers - BBC News

It may be possible to "soften-up" cancer cells before hitting them with chemotherapy drugs, researchers suggest.  
bbc.co.uk
over 6 years ago
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8

Chemotherapy does not improve quality of life in cancer patients at end of life, US study finds

Chemotherapy for patients with end stage cancer did not improve quality of life in those with poor or moderate performance status and worsened it in those with good performance status, US researchers have found.1  
feeds.bmj.com
about 6 years ago
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3

A comparison of platinum-based and non-platinum-based chemotherapy regimens for the treatment of small cell lung cancer | Cochrane

Do patients with small cell lung cancer (SCLC) who receive platinum-based chemotherapy treatment live longer than those who receive non-platinum-based chemotherapy treatment?  
cochrane.org
about 6 years ago
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13

Effective ovarian cancer treatment is underused, US study finds

Six years after the US National Cancer Institute issued a special clinical announcement encouraging the use of intraperitoneal and intravenous chemotherapy for ovarian cancer, less than half of eligible women were being treated with it, a new study has found.1  
feeds.bmj.com
about 6 years ago
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2

Interventions for leg cramps during pregnancy | Cochrane

Leg cramps are experienced as sudden, intense involuntary contractions of the leg muscles. They are a common problem in pregnancy, especially in the third trimester. They are painful and can interfere with daily activities, disrupt sleep, and reduce quality of life. Various interventions have been used during pregnancy to treat leg cramps, including drug, electrolyte (magnesium, calcium, sodium) and vitamin therapies, and non-drug therapies such as muscle stretching. The goal of this review was to find out what is effective and safe for treating leg cramps during pregnancy.  
cochrane.org
about 6 years ago
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8

Oncologic Emergencies Part I: Pearls and Pitfalls - emdocs

A great review of emergencies caused by metastatic cancer, chemotherapy, and radiation  
emdocs.net
about 6 years ago
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11

Transcutaneous electrical nerve stimulation (TENS) for phantom pain and stump pain following amputation in adults | Cochrane

Pain may present in a body part that has been amputated (phantom pain) or at the site of amputation (stump pain), or both. Phantom pain and stump pain are complex conditions and affect up to 80% of amputees.The underlying causes are not fully understood. Drug therapy is the most common treatment yet the condition remains poorly managed. The need for non-drug interventions has been recognised and TENS may have an important role to play.  
cochrane.org
about 6 years ago
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11

Nutritional support in children and young people with cancer undergoing chemotherapy | Cochrane

The provision of safe, appropriate and effective nutritional support for children and young people undergoing treatment for cancer is now well recognised as an important part of their care. It may help to reverse malnutrition seen at diagnosis, prevent malnutrition associated with the cancer, promote weight gain and growth and improve quality of life. Nutritional support may be provided by one of two methods: intravenous nutritional liquids delivered through a central or peripheral vein which bypass the gut (parenteral nutrition); or nutritional liquids or solids that pass through any part of the gut, regardless of method of delivery (e.g. orally or via a tube; enteral nutrition).  
cochrane.org
about 6 years ago
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7

Barium enema in a Hirschsprung's disease

Prepare for USMLE,UK,CANADIAN,AUSTRALIAN, NURSING & OTHER MEDICAL BOARD examinations around the globe with us.Understand the basics, concepts and how to answ...  
youtube.com
about 6 years ago
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12

Polypharmacy: An Obvious Problem in Need of Attention

A review paper questions the indefinite prescription of the big four cardiac drugs, reminding Dr Mandrola of David Foster Wallace's "This is Water" commencement speech challenging us to choose what to pay attention to.  
medscape.com
about 6 years ago