KlinefelterSyndrome

This is the presence of an extra X chromosome in males to give (47,XXY).    Epidemiology 1 in 1000 male live births   Clinical features Usually diagnosed in childhood when there is: Clumsyness Learning difficulties (usually mild) Typically intellectual ability is reduced y 10-20 IQ points, but still within the normal range. More susceptible to behavioural and psychological problems.