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PharmaceuticalPreparations

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3
201

Peri-arrest Arrhythmias

A resource made to accompany an RLO on peri-arrest arrhythmias I designed as part of my Doctors as Teachers project at Peninsula. It describes the assessment and management of peri-arrest arrhythmias as well as pharmacology of certain drugs used in their management. Hope you find it useful x  
Hope Raybould
almost 9 years ago
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3
342

Analgesics

ANALGESICS: THEIR PHARMACOLOGY AND THERAPEUTICS Pain is a common problem, and it is essential that doctors know how to treat it. It is recognised that many psychosocial factors affect people’s perception of pain, in particular of chronic pain. This revision article describes the pain ladder and the pharmacology and uses of the drugs it recommends.   THE W.H.O. PAIN LADDER1  
almostadoctor.com - free medical student revision notes
almost 8 years ago
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3
87

Anti-Histamines

Histamine H1-receptor antagonists These are not used in the management of respiratory conditions. They are mostly effective against mast cell activated inflammatory reactions. In asthma, mast cells are involved in the early stages of the reaction, but their role is not great enough to respond to therapeutic modification. These drugs are useful in patients with very mild atopic asthma, such as in cases of hay fever.  
almostadoctor.com - free medical student revision notes
almost 8 years ago
Www.bmj
3
135

Anticoagulation in atrial fibrillation

Atrial fibrillation increases the risk of stroke, which is a leading cause of death and disability worldwide. The use of oral anticoagulation in patients with atrial fibrillation at moderate or high risk of stroke, estimated by established criteria, improves outcomes. However, to ensure that the benefits exceed the risks of bleeding, appropriate patient selection is essential. Vitamin K antagonism has been the mainstay of treatment; however, newer drugs with novel mechanisms are also available. These novel oral anticoagulants (direct thrombin inhibitors and factor Xa inhibitors) obviate many of warfarin’s shortcomings, and they have demonstrated safety and efficacy in large randomized trials of patients with non-valvular atrial fibrillation. However, the management of patients taking warfarin or novel agents remains a clinical challenge. There are several important considerations when selecting anticoagulant therapy for patients with atrial fibrillation. This review will discuss the rationale for anticoagulation in patients with atrial fibrillation; risk stratification for treatment; available agents; the appropriate implementation of these agents; and additional, specific clinical considerations for treatment.  
bmj.com
almost 8 years ago
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3
35

Leukemia treatment

There are three main solutions to treat leukemia. Chemotherapy is a collection of drugs which target cells that rapidly multiply (a key characteristic in can...  
YouTube
over 7 years ago
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3
464

Learn: Antidepressant, Antipsychotic, Antianxiety Drugs (by lekhoa) - Memorize.com - Remember and Understand

Learn Antidepressant, Antipsychotic, Antianxiety Drugs facts using a simple interactive process (flashcard, matching, or multiple choice). Finally a format that helps you memorize and understand. Browse or search in thousands of pages or create your own page using a simple wizard. No signup required!  
memorize.com
over 7 years ago
Foo20151013 2023 184etvn?1444773944
3
135

Aspergillus and Human Health

Many may be familiar with aspergillosis as the infecting agent in acute cases where the patient is severely immunocompromised - but there is more to this fungus' repertoire. There are rare cases where the patient's immune system is overwhelmed by a large inhalation of spores e.g. after gardening, but these are insignificant in terms of total numbers effected. The following are far more common:- Aspergillus and other fungi are increasingly identified as the active agent in sinusitis - if you have cases that don't respond to antibiotics this is worth thinking about. Chronic pulmonary aspergillosis (CPA & aspergilloma) is an infection of immunocompetent people, causing respiratory difficulty, coughing and haemoptysis. The UK NHS has a specialist centre for these patients In Manchester (National Aspergillosis Centre (NAC)). NAC has particular expertise and extensive facilities for the diagnosis of CPA, ABPA, SAFS and use of systemic antifungal drugs. Allergic infection (Allergic Bronchopulmonary Aspergillosis - ABPA and chronic sinusitis) is thought to be heavily underdiagnosed and undertreated. ABPA is particularly common in Asthma, Cystic Fibrosis patients and those with bronchiectasis. There is estimated to be 25 000 cases in the UK alone. Many (50%) of the most severe asthma cases are sensitive to fungi (SAFS) - in particular Aspergillus. These tend to be the most unstable cases that don't respond to antibiotics and several studies have been published that show giving an antifungal helps reduce the use of steroids for these patients. Last but not least - Tuberculosis is on the rise in the UK and the rest of the world. It is estimated that 2% of cases progress to CPA and should be treated using an antifungal - this is usually not done until considerable time has passed and much damage has been done. In total it is estimated that many millions of people across the world suffer from aspergillus - ABPA - 5 million, Tb - 400 000 per year and Asthma (SAFS - 1 - 4 million cases in EU & US). Sinusitis cases may number many tens of millions worldwide. So - the next time you assume aspergillus infections and aspergillosis are rare and confined to those who are profoundly immunocompromised - think again! If you have a patient who has increasingly severe respiratory symptoms, doesn't respond to multiple courses of antibiotics then give aspergillus a thought. Browse around these articles for further information Aspergillus Website Treatment Section. NB For a broader look at the prevalence of fungal diseases worldwide the new charity Leading International Fungal Education (LIFE) website is worth looking at.  
Graham Atherton
almost 9 years ago
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2
96

Virtual Solutions to Real Problems: an Innovative Work Experience Support Programme

Poster presentation delivered at the AMEE 2009 Conference, focussing on work undertaken by St George’s committed to ensuring access to undergraduate healthcare courses is equitable. We recognise that the requirement for potential applicants to undertake and reflect on relevant work experience can be a barrier for under-represented groups. Such applicants are less likely to have social connections to support their preparation for application Building on our innovative use of e-learning technologies, we have developed a website for potential applicants offering essential information and guidance about finding and reflecting on work experience to support students’ preparation for application and interview Students from all backgrounds have access to information to support work experience and enhance their preparation for university application. The structured reflective tools include a journal template for download and online blogging, which were discussed during the session.  
Kirsty Wadsley
about 12 years ago
4
2
111

Differentiating, Dosing, and Combining Mood Stabilizing Drugs - Class of Mood Stabilizers

In this podcast, Drs. Andrew Cutler and Stephen M. Stahl differentiate between both pharmacological and clinical properties of different classes of mood stabilizers, and discuss examples of when one might choose one class of mood stabilizer over another.  
Neuroscience Education Institute
over 11 years ago
30081o
2
121

Liver pathology 2

Audio podcast outlining the pathological processes that occur in the liver including; infection, alcohol abuse, drugs toxicity, metabolic abnormalities, autoimmune processes and neoplasia.  
Podmedics
over 10 years ago
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2
22

Fears over statins use are 'misleading' - BBC News

A leading researcher on cholesterol-lowering statin drugs accuses critics of misleading the public about the dangers of taking them.  
BBC News
almost 8 years ago
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2
63

Different types of Inhaler

There are loads of types of inhalers! You need to be able to tell a patient how to use each type, and what type of drugs can go in each type.   With all inhalers, the amount of drug deposited on the mouth and pharynx is very high. Generally it is about 85% (even with good technique). This can improve to about 75% with different types of inhaler.   How a spacer works  
almostadoctor.com - free medical student revision notes
almost 8 years ago
Www.bmj
2
37

Ketamine helps a third of patients with treatment resistant depression, finds small UK study

A course of ketamine delivered intravenously could potentially be used to treat severe depression in patients who do not respond to other drugs, a UK study has found.  
bmj.com
almost 8 years ago
Www.bmj
2
55

Dermatitis herpetiformis

A 28 year old woman presented with a raised, red and intensely itchy rash on the extensor surface of her elbows and buttocks, in groups of small blisters. There was no history of trauma, atopy, or recent illness. She had no gastrointestinal symptoms or change in bowel habit and had not lost weight. No major medical or surgical history was noted and she was not taking drugs on a regular basis. Owing to the appearance and location of the rash, together with pruritus, dermatitis herpetiformis was suspected.  
bmj.com
almost 8 years ago
Www.bmj
2
71

US drug firm Pfizer seeks to buy UK company AstraZeneca

Pfizer, the US pharmaceutical giant whose drugs include atorvastatin (Lipitor) and sildenafil (Viagra), is seeking to buy the UK drug firm AstraZeneca for £52bn (€63bn; $90bn), which would be one of the largest acquisitions in the drug sector in recent years.  
bmj.com
almost 8 years ago